Cytotoxic Safety Cabinet

The Premium Solution for Cytotoxic Drug Processing

The Cytoculture Cytotoxic Safety Cabinet is the premium solution for cytotoxic/antineoplastic drug processing, providing the highest level of patient, pharmacist and environmental protection. This revolutionary product builds on experience of more than 20 years as a global leader in biological safety containment technology.

The unique demands of handling and preparing cytotoxic drugs for use in chemotherapy require a specialized cabinet. As cytotoxic drugs cannot be inactivated by chemical decontamination, Class II biosafety cabinets should not be used. With this in mind has developed a highly specialized range of cabinets designed especially for handling these potentially dangerous drugs.

With a range of specialist features incorporated into our Cytoculture Cytotoxic Safety Cabinets (CYT), Geneva Scientific brings you the ideal solution to your cytotoxic drug preparation challenges. Our CYT cabinets are designed to:

• Maintain the highest level of cleanliness within the work zone ensuring the best possible level of patient safety and product cleanliness.
• Provide the highest level of operator safety to protect you and your personnel from hazardous compounds used in cytotoxic drugs.
• Incorporate an advanced range of additional safety features, including a specialized Tri-Filter™ design, to guarantee the highest possible levels of environmental, operator and product protection. Contaminated air from the work zone is immediately filtered by a HEPA filter below the work zone to minimize the possibility of airborne contamination.
• Meet the requirements of all relevant safety standards for handling cytotoxic drugs (see technical specifications for details).
• Provide ISO Class 3 air cleanliness within the work zone. With an additional HEPA filter placed directly below the work zone, filters on our CYT cabinets can be changed without exposing the ambient environment and service personnel to potential hazards. This unique design allows contaminated filters to be removed easily, and all contaminated areas to be sterilized without compromising safety.

Designed and Built for Enhanced Usability

• All Cytotoxic Safety Cabinets are ergonomically designed for a high level of usability and efficiency. They incorporate a number of features to ensure operator comfort and enhanced productivity.
• The ergonomic angled front improves reach into the work zone and prevents glare off the sliding sash.
• The aesthetically pleasing stainless steel interior will never rust, chip or generate particles, enhancing operator and product protection.
• The interior back and side walls are fabricated from a single piece of stainless steel, with no joints or sharp corners.
• This makes the cabinet exceptionally easy to clean.
• Built-in warm white, electronically ballasted, 5000K lighting provides excellent illumination of the work zone to reduce operator fatigue. The reliable lighting system is zero-flicker and instant start.
• The front sliding sash window is motorized for movement, facilitating easy transfer of reagents and equipment into and out of the work zone.
• Spacious knee room is provided for the operator in a sitting position, ensuring comfort during use.
• The easily removable multi-piece stainless steel work surface construction increases cleanability.

Airflow

• "Blue Box" ULPA-Filtered Air
• "Red Box" Unfiltered / Potentially contaminated Air
• "Green Box" Room Air / Inflow Air

Enhanced Filtration System

• The enhanced filtration system is designed to provide the highest level of air quality within the work zone.
• CYT cabinets provide ISO Class 3 air cleanliness within the work zone (as per ISO 14644.1), significantly "cleaner" than the usual Class 5 classification on cabinets offered by the competition.
• A highly specialized Tri-Filter design incorporates two ULPA filters and an additional secondary HEPA exhaust filter, providing a world class level of air cleanliness to protect the operator
• Advanced minipleat separatorless HEPA and ULPA filter technology maximizes surface area. This energy efficient design reduces operating costs, extends filter life, and delivers increased laminar airflow uniformity, ensuring better product protection than conventional filters.
• The high quality ULPA filters (per IEST-RP-CC001.3) operate at typical efficiency of >99.999% at 0.1 to 0.3 micron sizes, providing superior product protection.
• The minipleat separatorless secondary exhaust HEPA filter (per IEST-RPCC001.3) fitted provides >99.99% efficiency at 0.3 microns.
• For enhanced safety the first exhaust filter can be changed easily without time consuming decontamination.
• An integral metal filter guard protects the HEPA and ULPA filters from accidental damage.
• Unique U-channels in work surface construction protect the main filters from liquid spills and small parts.

User-Friendly Control System

• The user-friendly Sentinel microprocessor-based control system, fitted to our CYT cabinets, supervises the operation of all cabinet functions. The controls are easily configurable to meet your requirements and comes equipped with a number of enhanced features to promote cabinet usability and safety.
• All critical cabinet airflow parameters can be monitored using the built-in accurate true airflow velocity sensing technology. Temperature compensated sensors ensure increased accuracy.
• Audible and visual alarms ensure product protection by alerting the user in the event of low airflow.
• Password-protected administration can be set to restrict access to the main menu ensuring that the cabinet cannot be operated by unauthorized personnel.
• Built-in solid state variable speed controllers, with integral RFI and noise filters, are superior to conventional “step” controllers and offer infinite adjustment from zero to maximum setting.

Cabinet Construction

• All products are manufactured to the highest quality, using the finest materials, for the most demanding laboratory applications.
• All components are designed for maximum chemical resistance and enhanced durability for a long service life, making CYT cabinets one of the most cost effective solutions on the market.
• The main body of the cabinet is constructed of industrial-grade electrogalvanized steel for durability and enhanced safety.
• All cabinet components are cleanroom compatible.
• The external structure of all our cabinets is coated with Isocide antimicrobial coating to protect against contamination and inhibit bacterial growth. Isocide eliminates 99.9% of surface bacteria within 24 hours of exposure to further ensure the cleanliness of the work zone.

Blower Efficiency

• Cytotoxic Safety Cabinets incorporate permanently lubricated direct drive centrifugal blowers. The energy efficient external rotor motor design reduces operating costs and has extremely low vibration.
• The blower system automatically maintains airflow as the filters become loaded, ensuring optimum efficiency and product protection without the need for constant manual adjustment.

Designed and Built to Exceed Safety Criteria

• At safety is of paramount importance. We take extra care in the design and construction of all cabinets to ensure all components used in our products meet or exceed all applicable safety requirements.
• Each cabinet is individually factory tested for safety and performance in accordance with international standards.
• Each unit is shipped with a documentation outlining the tests undertaken and the units individual results for each cabinet.
• All electrical components are UL listed or UL recognized, ensuring superior electrical safety for the operator.

Warranty

• Cytotoxic Safety cabinets include an extended 3 year warranty, excluding consumable parts and accessories. Contact your local Sales Representative for specific warranty details.

Customized to Meet Your Specific Needs

CYT cabinets can be configured to meet unique needs including:

• Lead shielding for nuclear medicine applications.
• An optional carbon filter impregnated with KI (potassium iodide) in place of the additional HEPA filter (this configuration does not protect service technicians when changing contaminated filters).

Available Documents

• Download Purchasing Specifications

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GENEVA SCIENTIFIC LLC       P.O. BOX 408 FONTANA WI 53125       PHONE: 262-245-1500       FAX: 262-245-6678

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